반응 #79445

반응 방정식

3,4-dichlorobenzoyl chloride

Fmoc-L-histidine

Fmoc-L-leucine

thiophene-2-carboxaldehyde

→

title compound

1-[1-(4-Chloro-phenyl)-methanoyl]-5-furan-2-yl-2-(1H-imidazol-4-ylmethyl)-pyrrolidine-2,4-dicarboxylic Acid

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실험 절차

Following the procedure of Example 28(a)-28(d), except beginning with Wang bound Fmoc-L-histidine (Trt) instead of Wang bound Fmoc-L-leucine, and substituting furan-2-carboxaldehyde for thiophene-2-carboxaldehyde, and substituting 4-chlorobenzoylchloride for 3,4-dichlorobenzoyl chloride, the title compound was prepared as a solid. MS [M+H]+444.8

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