반응 #79444

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3,4-dichlorobenzoyl chloride

Fmoc-L-histidine

Fmoc-L-leucine

thiophene-2-carboxaldehyde

→

title compound

5-Furan-2-yl-2-(1H-imidazol-4-ylmethyl)-1-(1-o-tolyl-methanoyl)-pyrrolidine-2,4-dicarboxylic acid

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실험 절차

Following the procedure of Example 28(a)-28(d), except beginning with Wang bound Fmoc-L-histidine (Trt) instead of Wang bound Fmoc-L-leucine, and substituting furan-2-carboxaldehyde for thiophene-2-carboxaldehyde, and substituting o-toluoyl chloride for 3,4-dichlorobenzoyl chloride, the title compound was prepared as a solid. MS [M+H]+424.4

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