반응 #792146

반응 방정식

(E)-1-(4-hydroxybenzo[d][1,3]dioxol-5-yl)-3-(pyridin-2-yl)prop-2-en-1-one

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title compound

수율 59.6%

1-(4-hydroxybenzo[d][1,3]dioxol-5-yl)-3-(pyridin-2-yl)propan-1-one

수율 59.6%

용매

methanol

반응 조건

후처리

1. 1
   기타to give a yellow solution
2. 2
   여과The reaction mixture was filtered
3. 3
   기타evaporated
4. 4
   세척the solid residue was washed with diethylether
5. 5
   기타dried

실험 절차

(E)-1-(4-hydroxybenzo[d][1,3]dioxol-5-yl)-3-(pyridin-2-yl)prop-2-en-1-one (0.5 g, 1.857 mmol) was added to methanol (50 ml) to give a yellow solution. Palladium on carbon (0.05 g) was added. Product was hydrogenated while stirring till conversion was completed (checked by TLC). The reaction mixture was filtered, evaporated and the solid residue was washed with diethylether, and dried to yield 0.3 g (57%) of the title compound.

출처