반응 #78541

반응 방정식

3-(4-cyanophenyl)propionic acid

3-amino-4-methylaminobenzoic acid-N-(2-pyridyl)-N-(2-ethoxycarbonylethyl)amide

→

1-Methyl-2-[2-(4-cyanophenyl)ethyl]benzimidazol-5-yl-carboxylic acid-N-(2-pyridyl)-N-(2-ethoxycarbonylethyl)amide

수율 22.0%

용매

dichloromethane methanol

반응 조건

실험 절차

Prepared analogously to Example 149a from 3-(4-cyanophenyl)propionic acid and 3-amino-4-methylaminobenzoic acid-N-(2-pyridyl)-N-(2-ethoxycarbonylethyl)amide. Yield: 22% of theory; Rf value: 0.68 (silica gel; dichloromethane/methanol=19:1).

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