반응 #78451

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6-bromo-4-(3-isopropoxy-phenyl)-2-methoxy-quinoline

(6-chloro-pyridin-3-yl)-(3-methyl-3H-imidazol-4-yl)-methanone

→

title compound

6-[(6-Chloro-Pyridin-3-yl)-Hydroxy-(3-Methyl-3H-Imidazol-4-yl)-Methyl]-4-(3-Isopropoxy-Phenyl)-1H-Quinolin-2-One

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실험 절차

Following the same procedure as that described in example 1E, 6-bromo-4-(3-isopropoxy-phenyl)-2-methoxy-quinoline (238.4 mg, 0.640 mmol) and (6-chloro-pyridin-3-yl)-(3-methyl-3H-imidazol-4-yl)-methanone (156 mg, 0.705 mmol) generated the title compound of 34C (80 mg, 24% yield).

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