반응 #78421

반응 방정식

2-methylbenzoic acid methyl ester

N-bromosuccinimide

AIBN

→

2-bromomethylbenzoic acid methyl ester

title compound

용매

tetrachlorocarbon

반응 조건

후처리

1. 1
   온도the mixture was refluxed for 30 minutes
2. 2
   여과cinnamoic acid that appeared were filtered off
3. 3
   농축the filtrate was concentrated
4. 4
   workup.DISTILLATIONThe residue was purified by distillation under reduced pressure

실험 절차

To a solution of 2-methylbenzoic acid methyl ester (33.0 g) in tetrachlorocarbon (440 ml) were added N-bromosuccinimide (43.0 g) and AIBN (2,2′-azobisisobutyronitrile, 361 mg) and the mixture was refluxed for 30 minutes. The reaction mixture was cooled down to 0° C. and cinnamoic acid that appeared were filtered off and the filtrate was concentrated. The residue was purified by distillation under reduced pressure to give the title compound having the following physical data (28.0 g, colorless oil).

출처