반응 #78223

ord-f03d6521fe21468caf92eef68013cb3c

반응 방정식

COC(=O)c1ccc(NC(=N)N)cc1OC.O=C(O)C(F)(F)F
methyl 4-guanidino-2-methoxybenzoate trifluoroacetate
Cl
hydrochloric acid
→
COc1cc(NC(=N)N)ccc1C(=O)O.Cl
title compound
COc1cc(NC(=N)N)ccc1C(=O)O.Cl
4-Guanidino-2-methoxybenzoic acid hydrochloride

반응물

COC(=O)c1ccc(NC(=N)N)cc1OC.O=C(O)C(F)(F)F
methyl 4-guanidino-2-methoxybenzoate trifluoroacetate
Cl
hydrochloric acid

시약

없음

반응 조건

온도
80°CELSIUS
상세 조건
See reaction.notes.procedure_details.

후처리

  1. 1
    기타The solvent was evaporated

실험 절차

384 mg of methyl 4-guanidino-2-methoxybenzoate trifluoroacetate was dissolved in 8 ml of 3 M hydrochloric acid, and they were stirred at 80° C. for 2.5 hours. The solvent was evaporated to obtain the title compound.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US06710056B2uspto-grants-2004_03