반응 #78197

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3-hydroxy-4-iodobenzonitrile

potassium carbonate

ethyl acetate

t-butyl(2-bromoethyl) carbamate

dimethylformamide

→

title compound

3-[2-(t-Butoxycarbonylamino)ethoxy]-4-iodobenzonitrile

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실험 절차

18.5 g (82.6 mmol) of t-butyl(2-bromoethyl) carbamate was dissolved in 200 ml of dimethylformamide (DMF). 10.1 g (41.3 mmol) of 3-hydroxy-4-iodobenzonitrile and 5.7 g (41.3 mmol) of potassium carbonate were added to the obtained solution, and they were stirred at 75° C. for 3 hours. After the treatment with ethyl acetate as the extracting solvent by an ordinary method, the title compound was obtained.

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