반응 #78196

반응 방정식

3-hydroxybenzoic acid

iodine monochloride

→

title compound

3-Hydroxy-4-iodobenzoic acid

용매

acetic acid

반응 조건

후처리

1. 1
   기타the solvent was evaporated under reduced pressure
2. 2
   세척The residue was washed with 500 ml of 1% aqueous sodium thiosulfate solution twice
3. 3
   건조with 500 ml of water twice and then dried to solid at 80° C. under reduced pressure

실험 절차

30.0 g (217 mmol) of 3-hydroxybenzoic acid was dissolved in 200 ml of acetic acid. 53.0 g (326 mmol) of iodine monochloride was added to the obtained solution at room temperature. They were stirred at 45° C. for 15 hours and then the solvent was evaporated under reduced pressure. The residue was washed with 500 ml of 1% aqueous sodium thiosulfate solution twice and with 500 ml of water twice and then dried to solid at 80° C. under reduced pressure to obtain the title compound.

출처