반응 #78154

반응 방정식

7-acetamino-1-chloro-4-(4-pyridylmethyl)-phthalazine

3-chloroaniline

→

7-Acetamino-1-(3-chloroanilino)-4-(4-pyridylmethyl)phthalazine hydrochloride

용매

1-butanol

반응 조건

후처리

1. 1
   여과ethanol and filtration lead to the title compound

실험 절차

By analogy with Example 25, 300 mg (0.96 mmol) 7-acetamino-1-chloro-4-(4-pyridylmethyl)-phthalazine is reacted in 3.9 ml 1-butanol with 302 μl (2.88 mmol) 3-chloroaniline. Suspension of the raw product in 1 ml boiling ethanol and filtration lead to the title compound: HPLC: tRet(Grad5-40)=11.3; FAB MS (M+H)+=404.

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