반응 #77985

반응 방정식

t-butyl 3-hydroxy-5-methyl-4-nitrophenylacetate

→

title compound

수율 91.1%

t-Butyl 4-amino-3-hydroxy-5-methyl-phenylacetate

수율 91.1%

용매

ethanol

반응 조건

후처리

1. 1
   여과After 4 hours the mixture was filtered through a pad of celite
2. 2
   기타the filtrate was evaporated

실험 절차

A solution of t-butyl 3-hydroxy-5-methyl-4-nitrophenylacetate (0.47 g, Reference Example 11) in ethanol (25 mL) was treated with palladium on charcoal (approximately 0.08 g, 10%) and stirred under a hydrogen atmosphere. After 4 hours the mixture was filtered through a pad of celite and the filtrate was evaporated to give the title compound (0.38 g) as a green oil.

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