반응 #77755

ord-39e77625a9e9404ca045647ef679cbc1

반응 방정식

CC(C)(C)OC(=O)N1CCCc2cc(OCC=CCBr)ccc21
6-(4-Bromo-but-2-enyloxy)-3,4-dihydro-2H-quinoline-1-carboxylic acid tert-butyl ester
C=CCNC
N-allyl-methylamine
→
C=CCN(C)CC=CCOc1ccc2c(c1)CCCN2C(=O)OC(C)(C)C
6-[4-(Allyl-methyl-amino)-but-2-enyloxy]-3,4-dihydro-2H-quinoline-1-carboxylic acid tert-butyl ester

반응물

CC(C)(C)OC(=O)N1CCCc2cc(OCC=CCBr)ccc21
6-(4-Bromo-but-2-enyloxy)-3,4-dihydro-2H-quinoline-1-carboxylic acid tert-butyl ester
C=CCNC
N-allyl-methylamine

시약

없음

반응 조건

상세 조건
See reaction.notes.procedure_details.

실험 절차

In analogy to example 2.6, 6-(4-Bromo-but-2-enyloxy)-3,4-dihydro-2H-quinoline-1-carboxylic acid tert-butyl ester and N-allyl-methylamine were converted to yield 6-[4-(Allyl-methyl-amino)-but-2-enyloxy]-3,4-dihydro-2H-quinoline-1-carboxylic acid tert-butyl ester as colorless oil, MS: 373 (MH+).

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US06706751B2uspto-grants-2004_03