반응 #77620

반응 방정식

1-(4-bromo-2-thienyl)-1-propanone

(3-carboxypropyl)triphenylphosphonium bromide

potassium tert-butoxide

→

desired product

(E)-5-(4-Bromo-2-thienyl)-4-heptenoic Acid

반응 조건

실험 절차

In a manner similar to that of Example 6(i), by reaction of 16 g (73 mmol) of 1-(4-bromo-2-thienyl)-1-propanone with 47 g (109 mmol) of (3-carboxypropyl)triphenylphosphonium bromide and 24.6 g (219 mmol) of potassium tert-butoxide, the desired product is obtained in the form of an orange-coloured solid (m=16.7 g; Y=80%).

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