반응 #77429

반응 방정식

propionamide

N-[4-(4-hydroxy-phenoxy)-benzyl]-propionamide

5-bromo-5-(2-ethoxy-ethyl)-pyrimidine-2,4,6-trione

dec-5-ene

PTBD

→

N-(4-{4-[5-(2-Ethoxy-ethyl)-2,4,6trioxo-hexahydro-pyrimidin-5-yloxy]phenoxy}-benzyl)-propionamide

용매

acetonitrile

반응 조건

실험 절차

Following the procedure outlined for the preparation of Example 1, N-[4-(4-hydroxy-phenoxy)-benzyl]-propionamide (0.13 g, 0.47 mmol) was reacted with 5-bromo-5-(2-ethoxy-ethyl)-pyrimidine-2,4,6-trione (0.13 g, 0.48 mmol), 1,5,7-trazabicyclo[4.4.0]dec-5-ene bound to polystyrene crosslinked with 2% DVB (PTBD, Fluka, 0.31 g) and 1.55 mL of acetonitrile, benzyl)-propionamide (0.060 g) as a colorless solid.

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