반응 #77095

ord-d226ff651b4f4417a703561a49ccdd70

반응 방정식

COc1ccc(CC2c3c(OC)ccc(O)c3CCN2CC(=O)NCc2ccccn2)cc1OC
2-[1-(3,4-dimethoxy-benzyl)-5-hydroxy-8-methoxy-3,4-dihydro-1H-isoquinolin-2-yl]-N-(pyridin-2-yl-methyl)-acetamide
CC(C)Br
isopropyl bromide
→
COc1ccc(CC2c3c(OC)ccc(OC(C)C)c3CCN2CC(=O)NCc2ccccn2)cc1OC
2-[1-(3,4-dimethoxy-benzyl)-5-isopropoxy-8-methoxy-3,4-dihydro-1H-isoquinolin-2-yl]-N-(pyridin-2-yl-methyl)-acetamide

반응물

COc1ccc(CC2c3c(OC)ccc(O)c3CCN2CC(=O)NCc2ccccn2)cc1OC
2-[1-(3,4-dimethoxy-benzyl)-5-hydroxy-8-methoxy-3,4-dihydro-1H-isoquinolin-2-yl]-N-(pyridin-2-yl-methyl)-acetamide
CC(C)Br
isopropyl bromide

시약

없음

반응 조건

상세 조건
See reaction.notes.procedure_details.

실험 절차

prepared by reaction of 2-[1-(3,4-dimethoxy-benzyl)-5-hydroxy-8-methoxy-3,4-dihydro-1H-isoquinolin-2-yl]-N-(pyridin-2-yl-methyl)-acetamide with isopropyl bromide

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US06703392B2uspto-grants-2004_03