반응 #76945

ord-4aa4730e5e27439b9e6b26c4715f8035

반응 방정식

CCC(c1ccccc1)C1NCCc2cc(OC)c(OC)cc21
1-(1-Phenyl-propyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline
O=C(Br)CBr
2-bromoacetyl bromide
NCc1ccccn1
2-picolylamine
→
CCC(c1ccccc1)C1c2cc(OC)c(OC)cc2CCN1CC(=O)NCc1ccccn1
2-[1-(1-Phenyl-propyl)-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]-N-(pyridin-2-yl-methyl)-acetamide

반응물

CCC(c1ccccc1)C1NCCc2cc(OC)c(OC)cc21
1-(1-Phenyl-propyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline
O=C(Br)CBr
2-bromoacetyl bromide
NCc1ccccn1
2-picolylamine

시약

없음

반응 조건

상세 조건
See reaction.notes.procedure_details.

실험 절차

prepared by reaction of 1-(1-Phenyl-propyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline and 2-bromoacetyl bromide with 2-picolylamine

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US06703392B2uspto-grants-2004_03