반응 #76911

ord-6fb07f005c5a4241bd25776e35f45a43

반응 방정식

COc1ccc(CC2NCCc3cc(OC)c(OC)cc32)cc1OC
1-(3,4-Dimethoxy-benzyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline
O=C(Br)CBr
2-bromoacetyl bromide
NCc1ccccn1
2-picolylamine
→
COc1ccc(CC2c3cc(OC)c(OC)cc3CCN2CC(=O)NCc2ccccn2)cc1OC
2-[1-(3,4-Dimethoxy-benzyl)-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]-N-(pyridin-2-yl-methyl)-acetamide

반응물

COc1ccc(CC2NCCc3cc(OC)c(OC)cc32)cc1OC
1-(3,4-Dimethoxy-benzyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline
O=C(Br)CBr
2-bromoacetyl bromide
NCc1ccccn1
2-picolylamine

시약

없음

반응 조건

상세 조건
See reaction.notes.procedure_details.

실험 절차

prepared by reaction of 1-(3,4-Dimethoxy-benzyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline and 2-bromoacetyl bromide with 2-picolylamine

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US06703392B2uspto-grants-2004_03