반응 #76891

ord-0e1c322a2c1a423d8853b894db257314

반응 방정식

COc1ccc(CC2NCCc3cc(OC)c(OC)cc32)cc1
1-(4-Methoxy-benzyl)-6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinoline
O=C(Br)CBr
2-bromoacetyl bromide
NCc1ccccc1
benzylamine
→
COc1ccc(CC2c3cc(OC)c(OC)cc3CCN2CC(=O)NCc2ccccc2)cc1
2-[1-(4-Methoxy-benzyl)-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]-N-benzyl-acetamide

반응물

COc1ccc(CC2NCCc3cc(OC)c(OC)cc32)cc1
1-(4-Methoxy-benzyl)-6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinoline
O=C(Br)CBr
2-bromoacetyl bromide
NCc1ccccc1
benzylamine

시약

없음

반응 조건

상세 조건
See reaction.notes.procedure_details.

실험 절차

prepared by reaction of 1-(4-Methoxy-benzyl)-6,7-dimethoxy-1,2,3,4-tetrahydro-isoquinoline and 2-bromoacetyl bromide with benzylamine

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US06703392B2uspto-grants-2004_03