반응 #76838

반응 방정식

trifluoroacetic acid

(R)-9-[2-(N-Boc-L-valyloxymethyl)-4-(stearoyloxy)butyl]guanine

→

trifluoracetate

title compound

(R)-9-[2-(L-Valyloxymethyl)-4-(stearoyloxy)butyl]guanine

반응 조건

후처리

1. 1
   기타evaporated to a small volume
2. 2
   기타was obtained

실험 절차

Chilled trifluoroacetic acid (2.0 g) was added to (R)-9-[2-(N-Boc-L-valyloxymethyl)-4-(stearoyloxy)butyl]guanine (180 mg; 0.25 mmol) and the solution kept at room temperature for 1 h, evaporated to a small volume, and lyophilized repeatedly with dioxane until a white amorphous powder was obtained. The yield of title compound, obtained as the trifluoracetate salt, was quantitative.

출처