반응 #76821

반응 방정식

(CF3)2CFOCF2CF2I

→

(CF3)2CFOCF2CHF2

수율 80.0%

용매

isopropanol

isopropanol

반응 조건

후처리

1. 1
   기타After the exothermic reaction
2. 2
   workup.DISTILLATIONThe reaction mixture was then distilled
3. 3
   기타of less then 80° C. was collected
4. 4
   세척This fraction was washed with an aqueous HCl solution
5. 5
   workup.DISTILLATIONdistilled over conc. H2SO4

실험 절차

A solution of (CF3)2CFOCF2CF2I (21.3 g) in isopropanol (8 mL) was added dropwise to a suspension of Al chips (1 g) and HgCl2 (0.4 g) in isopropanol (30 mL). After the exothermic reaction was completed, the reaction mixture was stirred for 1 hour at 55° C. The reaction mixture was then distilled and a fraction with a b.p. of less then 80° C. was collected. This fraction was washed with an aqueous HCl solution and then distilled over conc. H2SO4 to give (CF3)2CFOCF2CHF2 (11.8 g, 80% yield), b.p. 44 to 46° C. The 1H and 19F NMR were in accord with the assigned structure:

출처