반응 #76665

반응 방정식

1,4-phenylenediacetonitrile

hydrogen

→

title compound

2-[4-(2-Aminoethyl)phenyl]ethylamine

2-[4-(2-aminoethyl)cyclohexyl]ethylamine

용매

acetic acid

반응 조건

후처리

1. 1
   기타Into a 250 mL reduction vessel were placed
2. 2
   여과filtered through a Celite® cake
3. 3
   농축the filtrate was concentrated under reduced vacuum

실험 절차

Into a 250 mL reduction vessel were placed 1,4-phenylenediacetonitrile (2 g, 12.8 mmol), acetic acid (95 mL), and platinum oxide (0.25 g) and the mixture was heated at 60° C. under 60 psi (413.7 kPa) of hydrogen gas for 6 hours. The reaction was cooled to room temperature and filtered through a Celite® cake and the filtrate was concentrated under reduced vacuum to give the intermediate title compound, 2-[4-(2-aminoethyl)cyclohexyl]ethylamine, (3.7 g, 100%) as an oil. Electron spray M.S. 171 (M*+1).

출처