반응 #76376

ord-2d89c4a6c19742cea11d66a9ead29487

반응 조건

상세 조건
See reaction.notes.procedure_details.

후처리

  1. 1
    기타quenched with water
  2. 2
    추출extracted with ethyl acetate:hexane (1:1)
  3. 3
    세척washed with brine, over MgSO4
  4. 4
    농축concentrated in vacuo

실험 절차

To the commercially available 6-bromo-naphthalene-2-ol (1) (1 equi.) and benzyl bromide (2) (1 equi.) in DMF (3mL/mmole), cesium carbonate (1.25 equi.) was added at room temperature. The reaction mixture was stirred at that temperature for 24 h, quenched with water, extracted with ethyl acetate:hexane (1:1), washed with brine, over MgSO4, and concentrated in vacuo.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US06703082B1uspto-grants-2004_03