반응 #7626

반응 방정식

acetylchloride

2-amino-pyrimidine

cyclohexylisonitrile

acetaldehyde

→

1-acetyl-3-cyclohexylamino-2-methyl-imidazo[1,2-a]pyrimidin-1-ium chloride

용매

perchloric acid

반응 조건

실험 절차

Example 24 was carried out in accordance with the general directions for synthesis in process step a) from 1.0 ml (0.1 mmol) 2-amino-pyrimidine (0.1 M, DCM), 0.575 ml (0.115 mmol) cyclohexylisonitrile solution (0.2 M, DCM), 0.500 ml (0.15 mmol) acetaldehyde solution (0.3 M, DCM) and 10 μl perchloric acid (w=20%) and in process step c) and d) by reacting the resultant reaction product with 0.4 mmol acetylchloride.

출처