반응 #7621
ord-1cc3531c804049d985d00a34b502b64b
반응 방정식
acetylchloride
2-amino-pyrimidine
cyclohexylisonitrile
pyridine-2-carbaldehyde
→
1-acetyl-3-cyclohexylamino-2-pyridin-2-yl-imidazo[1,2-a]pyrimidin-1-ium chloride
반응 조건
상세 조건
See reaction.notes.procedure_details.
실험 절차
Example 19 was carried out in accordance with the general directions for synthesis in process step a) from 1.0 ml (0.1 mmol) 2-amino-pyrimidine (0.1 M, DCM), 0.575 ml (0.115 mmol) cyclohexylisonitrile solution (0.2 M, DCM), 0.500 ml (0.15 mmol) pyridine-2-carbaldehyde solution (0.3 M, DCM) and 10 μl perchloric acid (w=20%) and in process step c) and d) by reacting the resultant reaction product with 0.4 mmol acetylchloride.