반응 #75642

반응 방정식

4-chloroaniline

ethylglyoxalate

styrene

trifluoroacetic acid

→

Compound 5

수율 94.0%

6-chloro-4-phenyl-1,2,3,4-tetrahydroquinoline-2-carboxylic Acid Ethyl Ester

수율 94.0%

용매

acetonitrile

반응 조건

실험 절차

Compound 5 was prepared in a yield of 94% by the basic process from 5.0 mmol 4-chloroaniline, 5.5 mmol ethylglyoxalate solution (50% toluene), 15.0 mmol styrene and 5.0 mmol trifluoroacetic acid in 30.0 ml acetonitrile.

출처