반응 #75438
ord-32ee0f1e9343437cab24338b7c57f84b
반응 방정식
5-methyl-4-hexenoic acid
diazomethane
→
title product
Methyl 5-methyl-4-hexenoate
반응 조건
상세 조건
See reaction.notes.procedure_details.
후처리
- 1기타The solvent was then evaporated under vacuum
실험 절차
Freshly prepared diazomethane in ether was added to an ice-cooled solution of 5-methyl-4-hexenoic acid (4.5 g, 35.16 mmol) in ether (10 mL) until the solution became slightly yellow in color. The solvent was then evaporated under vacuum to afford the title product as a colorless liquid in near quantitative yield (4.90 g). This product was used in the next reaction step without further purification. 1H NMR (CDCl3) δ1.62 & 1.68[2s, 6H, C(CH3)2], 2.30[m, 4H, (CH2)2], 3.69(s, 3H, COOCH3) and 5.07(t, 1H, CH).