반응 #75142

반응 방정식

1-(3-chloropropyl)-1,3-dihydro-3-(1-methylethenyl)-2H-benzimidazol-2-one

hydrochloric acid

→

1-(3-chloropropyl)-1,3-dihydro-2H-benzimidazol-2-one

수율 90.0%

용매

ethanol

반응 조건

후처리

1. 1
   기타The reaction mixture is evaporated
2. 2
   기타the solid residue is crystallized from 2-propanol

실험 절차

A solution of 13 parts of 1-(3-chloropropyl)-1,3-dihydro-3-(1-methylethenyl)-2H-benzimidazol-2-one in 6 parts of a hydrochloric acid solution and 40 parts of ethanol is stirred for 2 hours at room temperature. The reaction mixture is evaporated and the solid residue is crystallized from 2-propanol, yielding 9.5 parts (90%) of 1-(3-chloropropyl)-1,3-dihydro-2H-benzimidazol-2-one; mp. 115° C.

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