반응 #74953

반응 방정식

chloromethyl pivalate

N-(2-chloro-benzyl)-2-(2-thienyl)ethylamine

→

title compound

수율 51.0%

5-(2-chloro-benzyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine hydrochloride

수율 51.0%

용매

dimethylsulfoxide

반응 조건

실험 절차

66.5 g (0.44 M) chloromethyl pivalate is reacted by heating, for 3 hours, with a solution of 103 g (0.4 M) N-(2-chloro-benzyl)-2-(2-thienyl)ethylamine in 300 ml dimethylsulfoxide, to give the title compound in a yield of 51%.

출처