반응 #74880

반응 방정식

stearic acid chloride

sorbitol

hydrochloric acid

→

sorbitol stearate

용매

toluene

pyridine

반응 조건

후처리

1. 1
   workup.ADDITIONare added dropwise to this mixture over 25 minutes
2. 2
   기타(at approx. 110° C.)
3. 3
   기타for 1 hour
4. 4
   온도under reflux
5. 5
   온도After cooling
6. 6
   세척is then washed with water until neutral and
7. 7
   건조dried with dehydrated sodium sulphate
8. 8
   기타After concentration of the organic phase the sorbitol stearate crystallizes
9. 9
   기타It is recrystallized from methanol

실험 절차

411.5 g (1.358 mols) stearic acid chloride are dissolved in 3 l toluene and heated to 90° C. 41.23 g (0.22 mols) of sorbitol, dissolved in 200 ml pyridine are added dropwise to this mixture over 25 minutes. The solution is boiled (at approx. 110° C.) for 1 hour under reflux. After cooling, dilute hydrochloric acid is added to acidify the mixture, which is then washed with water until neutral and dried with dehydrated sodium sulphate. After concentration of the organic phase the sorbitol stearate crystallizes. It is recrystallized from methanol.

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