반응 #747461

ord-236a27772eda4c94b769fa3f800446c5

반응 방정식

CCOC(=O)C(C)c1ccc(N)c(N)c1
Ethyl 2-(3,4-diaminophenyl)propanoate
O=C(n1ccnc1)n1ccnc1
1,1′-carbonyldiimidazole
C1CCC2=NCCCN2CC1
DBU
→
CCOC(=O)C(C)c1ccc2[nH]c(=O)[nH]c2c1
Ethyl 2-(2,3-dihydro-2-oxo-1H-benzo[d]imidazol-5-yl)propanoate

반응물

CCOC(=O)C(C)c1ccc(N)c(N)c1
Ethyl 2-(3,4-diaminophenyl)propanoate
O=C(n1ccnc1)n1ccnc1
1,1′-carbonyldiimidazole
C1CCC2=NCCCN2CC1
DBU

시약

없음

용매

ClCCl
CH2Cl2

반응 조건

상세 조건
See reaction.notes.procedure_details.

실험 절차

A solution of Ethyl 2-(3,4-diaminophenyl)propanoate (217 mg, 1.04 mmol) in CH2Cl2 (4 mL) was added 1,1′-carbonyldiimidazole (189 mg) and DBU (330 mg, in CH2Cl2 (4 mL)) at room temperature.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US08084484B2uspto-grants-2011_12