반응 #74742

반응 방정식

2-methyl-3-buten-2-ol

methyl acetoacetate

2-methyl-3-buten-2-ol

2-methyl-2-hepten-6-one

aluminum triisopropylate

→

2-methyl-2-hepten-6-one

2-methyl-3-buten-2-ol

isoprene

반응 조건

후처리

1. 1
   workup.ADDITIONis introduced in the course of 18 hours
2. 2
   workup.DISTILLATIONby distillation when the reaction

실험 절차

7.5 g of aluminum triisopropylate and 50 g of a reaction product which contains 42 g of 2-methyl-2-hepten-6-one and 5 g of 2-methyl-3-buten-2-ol are heated at 150° C. in the reaction apparatus described in Example 1, and a mixture of 464 g of methyl acetoacetate and 430 g of 2-methyl-3-buten-2-ol is introduced in the course of 18 hours. On working up the mixture by distillation when the reaction has ceased, 490 g of 2-methyl-2-hepten-6-one, 95 g of unconverted 2-methyl-3-buten-2-ol, 13 g of acetone and 4 g of isoprene are obtained. The yield (448 g) is 89% of theory, based on methyl acetoacetate employed, and 90.1%, based on methylbutenol converted.

출처