반응 #747174

반응 방정식

2-amino-4,6-dichloro-3-methoxybenzoic acid methyl ester

triethyl orthoformate

→

4,6-dichloro-2-ethoxymethyleneamino-3-methoxybenzoic acid methyl ester

반응 조건

후처리

1. 1
   온도under reflux for 5 days
2. 2
   기타evaporated under reduced pressure

실험 절차

A solution of the 2-amino-4,6-dichloro-3-methoxybenzoic acid methyl ester (2-3) (6.35 g, 25.4 mmol) and triethyl orthoformate (60 mL, 361 mmol) was heated under reflux for 5 days. The solution was cooled to room temperature and evaporated under reduced pressure to afford the imidate, 4,6-dichloro-2-ethoxymethyleneamino-3-methoxybenzoic acid methyl ester (5-2), and starting material (7.80 g) as a brown oil; 5-2:2-3-9:1.

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