반응 #74701

반응 방정식

propionic acid

ammonium acetate

N-(benzotriazol-5-yl)naphth-2-amide

2-Methylsulphonyl-4-nitroaniline

propionic acid

sodium nitrite

→

N-(benzotriazol-5-yl)-1-hydroxy-4-(2-methylsulphonyl-4-nitrophenylazo)naphth-2-amide

용매

acetic acid

acetic acid

sulphuric acid

반응 조건

후처리

1. 1
   workup.ADDITIONThe mixture was poured onto ice
2. 2
   여과the product was filtered
3. 3
   기타crystallized in aqueous pyridine

실험 절차

2-Methylsulphonyl-4-nitroaniline (0.66 g) was diazotized in a mixture of 3:1 v/v glacial acetic acid:propionic acid (40 ml) by adding sodium nitrite (0.21 g) in concentrated sulphuric acid (2.5 ml) dropwise a 0° C. The resulting diazonium solution was added to N-(benzotriazol-5-yl)naphth-2-amide (1.0 g) dissolved in 3:1 v/v glacial acetic acid:propionic acid (100 ml) containing ammonium acetate (16.2 g) and the mixture was stirred at room temperature for one hour. The mixture was poured onto ice and the product was filtered and crystallized in aqueous pyridine. Yield 1.16 g, m.p. 260° decomp., λmax (methanol)=577 nm.

출처