반응 #74497

반응 방정식

compound 2

2,3,4,6-tetra-O-benzyl-D-glucopyranose

((4-bromo-1-methoxynaphthalen-2-yl)methoxy)-triisopropylsilane

compound 68b

((4-bromo-1-methoxynaphthalen-2-yl)methoxy)-triisopropylsilane

2,3,4,6-tetra-O-benzyl-D-glucopyranose

→

title compound

수율 85.0%

(1-Methoxy-4-((2S,3S,4R,5R,6R)-3,4,5-tris(benzyloxy)-6-(benzyloxymethyl)-tetrahydro-2H-pyran-2-yl)naphthalen-2-yl)methanol

수율 85.0%

반응 조건

실험 절차

With similar method described in Step 3 of Example 92, ((4-bromo-1-methoxynaphthalen-2-yl)methoxy)-triisopropylsilane (compound 68b, 21.3 g, 50.3 mmol) and 2,3,4,6-tetra-O-benzyl-D-glucopyranose (compound 2, 22.6 g, 41.9 mmol) were converted to title compound (25.3 g, 85%) as a white solid.

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