반응 #74495

반응 방정식

Bromine

1-hydroxy-2-naphthoic acid

compound 66

1-hydroxy-2-naphthoic acid

→

title compound

수율 92.1%

4-Bromo-1-hydroxy-2-naphthoic acid

수율 92.1%

용매

acetic acid

반응 조건

후처리

1. 1
   여과The resulting solid was filtered
2. 2
   기타dried in vacuo

실험 절차

Bromine (6.1 mL, 120 mmol) was added to a solution of 1-hydroxy-2-naphthoic acid (compound 66, 18.9 g, 100 mmol) in glacial acetic acid (250 mL). The mixture was stirred at room temperature overnight. The resulting solid was filtered and dried in vacuo to yield the title compound (24.6 g, 92%) as a white solid.

출처