반응 #742291

반응 방정식

(2S)-2-[(tert-butoxycarbonyl)-amino]-propyl pivaloate

HCl

dioxane

→

(2S)-2-aminopropyl-2,2-dimethylpropanoate hydrochloride

용매

EtOAc

반응 조건

후처리

1. 1
   기타the solvent was evaporated in vacuo
2. 2
   기타to give a solid
3. 3
   세척that was washed with Et2O
4. 4
   기타dried

실험 절차

To a solution of (2S)-2-[(tert-butoxycarbonyl)-amino]-propyl pivaloate (1.0 eq.) in EtOAc (0.6 M) was added 4N HCl in dioxane (10 eq.). The reaction mixture was stirred for 2.5 h and then the solvent was evaporated in vacuo to give a solid that was washed with Et2O and dried.

출처