반응 #742248

반응 방정식

(E)-3-(2-hydroxy-phenyl)-2-methyl-acrylic acid

citronellol

p-toluene-sulfonic acid

water

→

colourless oil

(E)-3-(2-Hydroxy-phenyl)-2-methyl-acrylic acid 3,7 dimethyl-oct-6-enyl ester

용매

cyclohexane

hexane

반응 조건

후처리

1. 1
   온도Then the reaction mixture was cooled down
2. 2
   세척washed
3. 3
   기타The organic phase was dried
4. 4
   여과filtered
5. 5
   기타evaporated to dryness
6. 6
   기타The resulting yellow oil was purified by chromatography

실험 절차

A solution of 6 0 g of (E)-3-(2-hydroxy-phenyl)-2-methyl-acrylic acid, 5.3 g of citronellol and 1 g of p-toluene-sulfonic acid in 150 ml of cyclohexane was refluxed for 6.5 hours using a water separator. Then the reaction mixture was cooled down, diluted with hexane and washed to neutrality with saturated sodium bicarbonate and water. The organic phase was dried, filtered and evaporated to dryness. The resulting yellow oil was purified by chromatography to yield 6.45 g of a colourless oil.

출처