반응 #73872

반응 방정식

Potassium hydroxide

4-Bromophenylacetonitrile

1,2-dibromoethane

→

title compound

1-(4-Bromo-phenyl)-cyclopropanecarbonitrile

용매

toluene

H2O

반응 조건

실험 절차

Potassium hydroxide (14.3 g, 255 mmol) was dissolved in H2O (5 mL) and toluene (40 mL). 4-Bromophenylacetonitrile (5.0 g, 25.5 mmol) and tetrabutylammonium bromide (0.41 g, 1.3 mmol) was added, followed by 1,2-dibromoethane (3.25 mL, 38 mmol) dropwise over 10 minutes. The reaction was stirred at room temperature for 2 hours and then worked-up to give the title compound.

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