반응 #737638

반응 방정식

1-Chloroethyl chloroformate

1-octadecanol

Pyridine

→

1-Chloroethyl octadecyl carbonate

용매

chloroform

반응 조건

후처리

1. 1
   온도maintaining the temperature below 10° C
2. 2
   세척was washed four times with 1N hydrochloric acid
3. 3
   건조The organic solution was dried with magnesium sulphate
4. 4
   기타the solvent was removed at reduced pressure

실험 절차

1-Chloroethyl chloroformate (7.15 g, 50 mmol) and 1-octadecanol (13.53 g, 50 mmol) were suspended in chloroform (100 ml) at 0° C. Pyridine (3.96 g, 50 mmol) was added dropwise during 20 minutes, maintaining the temperature below 10° C. After stirring at room temperature for 24 hours the reaction mixture was washed four times with 1N hydrochloric acid, once with a saturated sodium bicarbonate solution and finally twice with water. The organic solution was dried with magnesium sulphate and the solvent was removed at reduced pressure. Yield: 19 g.

출처