반응 #7373

ord-e844e5c076c84bcdb7aca1ff5d4592b9

반응 방정식

CCOC(=O)C(CCI)N=[N+]=[N-]
ethyl 2-azido-4-iodobutanoate
C[C@H](N)C(=O)OC(C)(C)C
L-alanine tert-butyl ester
→
C[C@@H](C(=O)OC(C)(C)C)N1CCC(N=[N+]=[N-])C1=O
title compound
C[C@@H](C(=O)OC(C)(C)C)N1CCC(N=[N+]=[N-])C1=O
tert-Butyl (2S)-2-(3-azido-2-oxopyrrolidin-1-yl)propanoate

반응물

CCOC(=O)C(CCI)N=[N+]=[N-]
ethyl 2-azido-4-iodobutanoate
C[C@H](N)C(=O)OC(C)(C)C
L-alanine tert-butyl ester
—
Intermediate 33

시약

없음

반응 조건

상세 조건
See reaction.notes.procedure_details.

실험 절차

Using ethyl 2-azido-4-iodobutanoate and L-alanine tert-butyl ester, and the procedure described for Intermediate 33, the title compound was prepared as a mixture of two diastereoisomers.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US07084139B2uspto-grants-2006_08