반응 #73621

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2-chlorobenzoyl chloride

2-amino-4-methylthiazole-5-carboxylic acid benzylamide

→

title compound

수율 13.0%

2-(2-Chlorobenzoylamino)-4-methylthiazole-5-carboxylic Acid Benzylamide

수율 13.0%

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실험 절차

Following the procedure as described in Example 2, making variations only as required to use 2-chlorobenzoyl chloride in place of benzoyl chloride to react with 2-amino-4-methylthiazole-5-carboxylic acid benzylamide, the title compound was obtained as a white solid in 13% yield; 1H NMR (CDCl3, 300 MHz) δ 7.78 (d, J=7.8 Hz, 1H), 7.46-7.27 (m, 8H), 5.95 (s, 1H), 4.57 (d, J=4.6 Hz, 2H), 2.33 (s, 3H); MS (ES+) m/z 386.1 (M+1).

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