반응 #735819

ord-8b3b296493e4403e8ce56ba4fb60b574

반응 방정식

Cc1ccc(S(=O)(=O)NNC(=O)c2ccc(C(C(N)=O)C(C)c3ccccc3N3CCCCC3)cc2)cc1
N1 -[4-[(1-(2-piperidino-phenyl)-ethyl)-aminocarbonylmethyl]benzoyl]-N2 -tosyl-hydrazine
O=C([O-])[O-].[Na+].[Na+]
sodium carbonate
→
CC(c1ccccc1N1CCCCC1)C(C(N)=O)c1ccc(C=O)cc1
4-[(1-(2-Piperidino-phenyl)-1-ethyl)-aminocarbonylmethyl]-benzaldehyde

반응물

Cc1ccc(S(=O)(=O)NNC(=O)c2ccc(C(C(N)=O)C(C)c3ccccc3N3CCCCC3)cc2)cc1
N1 -[4-[(1-(2-piperidino-phenyl)-ethyl)-aminocarbonylmethyl]benzoyl]-N2 -tosyl-hydrazine
O=C([O-])[O-].[Na+].[Na+]
sodium carbonate

시약

없음

용매

OCCO
ethylene glycol

반응 조건

상세 조건
See reaction.notes.procedure_details.

후처리

  1. 1
    기타The above compound was prepared by the

실험 절차

The above compound was prepared by the heating of crude N1 -[4-[(1-(2-piperidino-phenyl)-ethyl)-aminocarbonylmethyl]benzoyl]-N2 -tosyl-hydrazine with anhydrous sodium carbonate at 160°-170° C. in ethylene glycol [prepared from 4-[(1-(2-piperidino-phenyl)-ethyl)-aminocarbonylmethyl]-benzoic acid and tosyl-hydrazine with carbonyl diimidazole in tetrahydrofuran].

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US04735959uspto-grants-1988_04