반응 #732527

반응 방정식

25

1-bromo-5-methyl-hexane

triphenylphosphine

→

10

수율 81.0%

(5-methylhexyl)triphenylphosphonium bromide

수율 81.0%

용매

toluene

반응 조건

후처리

1. 1
   기타Then solvent was removed
2. 2
   세척the resulting crystal was washed with toluene (3 mL) and diethyl ether (3 mL)

실험 절차

A solution of 25 (2.30 g; 12.8 mmol) and triphenylphosphine (3.70 g; 14.1 mmol) was refluxed in toluene (12 mL) for 20 h. Then solvent was removed and the resulting crystal was washed with toluene (3 mL) and diethyl ether (3 mL) to give 4.57 g (10.4 mmol; 81% yield) of 10. m.p. 227-228° C.; 1H NMR (500 MHz, CD3CN) δ 0.82 (6H, d, J=6.6 Hz), 1.16 (2H, m), 1.42-1.52 (3H, m), 1.59 (2H, m), 3.30 (2H, m), 7.72 (12H, m), 7.85 (3H, m); 13C NMR (125 MHz, CD3CN) δ 22.7, 23.2, 28.4, 28.8, 28.9, 38.6, 131.2, 131.3, 134.7, 134.7, 136.0.

출처