반응 #730421

반응 방정식

potassium carbonate

decyl bromide

mercaptoethanol

→

2-(decylthio)ethanol

수율 94.0%

용매

acetone

반응 조건

후처리

1. 1
   기타partitioned between water and 80% hexane/ethyl acetate
2. 2
   세척The organic phase was washed with 2N sodium hydroxide
3. 3
   건조dried over magnesium sulfate
4. 4
   기타the volatiles removed under vacuum

실험 절차

Under nitrogen, to a suspension of potassium carbonate (27 g, 200 mmol) in acetone (100 ml) was added decyl bromide (10 ml, 50 mmol) and mercaptoethanol (4.4 ml, 63 mmol). The suspension was stirred at room temperature for 2 days, then partitioned between water and 80% hexane/ethyl acetate. The organic phase was washed with 2N sodium hydroxide, dried over magnesium sulfate, and the volatiles removed under vacuum to give 2-(decylthio)ethanol (10.2 g, 47 mmol) as a colorless liquid that was used without further purification.

출처