반응 #723013

반응 방정식

1,3-butadiene

3,4-dimethoxy-ω-nitrostyrene

hydroquinone

→

(+/−)-trans-1,2-dimethoxy-4-(2-nitrocyclohexyl) benzene

용매

toluene

반응 조건

후처리

1. 1
   기타at −70° C.
2. 2
   온도cooled
3. 3
   기타Some of the solvent is removed
4. 4
   기타a rotary evaporator
5. 5
   여과the resulting precipitate is filtered off with suction
6. 6
   기타recrystallized from ethanol

실험 절차

50.0 g of 3,4-dimethoxy-ω-nitrostyrene and 1.0 g (9.1 mmol) of hydroquinone are suspended in 200 ml of abs. toluene and, at −70° C., admixed with 55.0 g (1.02 mol) of liquid 1,3-butadiene. The mixture is stirred in an autoclave at 160° C. for 6 days and then cooled. Some of the solvent is removed using a rotary evaporator, and the resulting precipitate is filtered off with suction and recrystallized from ethanol. M.p.: 113.5-115.5° C.; Yield 76.3% of Th.

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