반응 #722491

반응 방정식

hydrochloric acid

1-(4-fluorophenyl)piperazine

3-(4,5,6,7-tetrahydro-2H-indazol-3-yl)propionic acid

4-(4-chlorophenyl)piperidine

→

3-(3-(4-(4-fluorophenyl)piperazin-1-yl)propyl)-2,4,5,6-tetrahydrocyclopentapyrazole dihydrochloride dihydrate

반응 조건

후처리

1. 1
   기타obtained

실험 절차

In the same manner as in Example 102 except that 3-(2,4,5,6-tetrahydrocyclopentapyrazol-3-yl)propionic acid obtained in Starting Material Synthesis Example 4 and 1-(4-fluorophenyl)piperazine were used instead of 3-(4,5,6,7-tetrahydro-2H-indazol-3-yl)propionic acid obtained in Starting Material Synthesis Example 1 and 4-(4-chlorophenyl)piperidine and then by a conventional treatment using hydrochloric acid, 3-(3-(4-(4-fluorophenyl)piperazin-1-yl)propyl)-2,4,5,6-tetrahydrocyclopentapyrazole dihydrochloride dihydrate was obtained, m.p. 228-230° C.

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