반응 #71795

반응 방정식

Methyl 3-oxopentanoate

Bromine

→

Methyl 4-bromo-3-oxopentanoate

용매

chloroform

반응 조건

후처리

1. 1
   온도cooling
2. 2
   세척The reaction solution was washed with saturated aqueous sodium bicarbonate solution
3. 3
   건조dried over anhydrous sodium sulfate
4. 4
   농축concentrated under reduced pressure
5. 5
   기타The resulting compound was used for the next reaction without purification

실험 절차

Methyl 3-oxopentanoate (1 g, 7.68 mmol) was dissolved in chloroform (30 mL). Bromine (0.4 mL, 7.80 mmol) was added under ice-cooling and the mixture was stirred for 40 minutes. The reaction solution was washed with saturated aqueous sodium bicarbonate solution, dried over anhydrous sodium sulfate and then concentrated under reduced pressure. The resulting compound was used for the next reaction without purification.

출처