반응 #712188
ord-abd7e8ad4bfd46fcaa945a1958fe69bf
반응 방정식
5-(tert-butoxycarbonyl)-5-azaspiro[2.4]heptane-6-carboxylic acid
ammonia
→
title compound
수율 78.0%
tert-Butyl 6-carbamoyl-5-azaspiro[2.4]heptane-5-carboxylate
수율 78.0%
반응 조건
상세 조건
See reaction.notes.procedure_details.
실험 절차
In analogy to the procedure described in Example 127 c), 5-(tert-butoxycarbonyl)-5-azaspiro[2.4]heptane-6-carboxylic acid (CAN 1454843-77-6, 112 mg, 464 μmol) was condensed with ammonia to give the title compound (87 mg, 78%) as colorless liquid, MS (EI): m/e=240.0 [M+].