반응 #70835

반응 방정식

6-chloronicotinic acid

SOCl2

→

desired product

수율 93.0%

6-Chloronicotinoyl chloride hydrochloride

수율 93.0%

반응 조건

후처리

1. 1
   온도to reflux for 2 h
2. 2
   기타The SOCl2 was evaporated to dryness

실험 절차

A solution of 6-chloronicotinic acid (10.00 g, 63.5 mmol) in SOCl2 (37 mL) was heated to reflux for 2 h. The SOCl2 was evaporated to dryness, to afford 12.56 g of the desired product (yield: 93%).

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