반응 #70439

반응 방정식

tert-butyl 4-[2-(4-cyano-3-fluorophenoxymethyl)pyridin-5-yl]piperidine-1-carboxylate

5-pentyl-2-bromopyrimidine

→

title compound

2-[4-[2-(4-Cyano-3-fluorophenoxymethyl)pyridin-5-yl]piperidin-1-yl]-5-pentylpyrimidine

반응 조건

실험 절차

The title compound was prepared from tert-butyl 4-[2-(4-cyano-3-fluorophenoxymethyl)pyridin-5-yl]piperidine-1-carboxylate (Example 13) (33 mg, 0.08 mmol) and 5-pentyl-2-bromopyrimidine (27 μL, 0.16 mmol) following a procedure analogous to that in Example 48 as a white crystal (24 mg, yield 65%).

출처